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What Happens When Your Body Clock is a Mess?

When you think about your “body clock,” it’s likely that the only thing you associate it with is your sleep schedule. But what if I told you that your “clock” is running in every cell of your body, every single day minute of the day?

It’s true. In fact, three scientists who contributed to this discovery received the Nobel Prize for it. And it’s well deserved.

It turns out that our circadian rhythm is critical to much more than our sleeping habits. Any mismatch between our lifestyle and our internal clock can affect any number of biological processes.

In the short-term you might find yourself feeling fuzzy, forgetful and out of sorts. You might even feel hungrier than usual… craving sweets and carbs.

But in the long-term?

If you tend to live “out of synch” with your natural circadian rhythm, it can seriously affect your health. Among other things, this includes an increased risk of heart disease, type 2 diabetes, obesity and cancer.

Mysterious Ways Your Body Clock Affects Your Health

Your body temperature, blood pressure, heart beat, energy levels, metabolism and hormones are all aligned with your daily rhythm.

For example, your blood pressure fluctuates over a 24-hour cycle – dropping to its lowest point at night and peaking at mid-morning.

However, just a short-term misalignment of your circadian rhythm interferes with that night-time dip in blood pressure. Instead, it could actually increase your sleeping blood pressure by about 5.6 points on the top number (systolic) and 1.9 on the bottom (diastolic). This can result in higher blood during wake periods, too.

When your internal clock gets out of whack it also increases certain inflammatory markers associated with heart disease and poor health. Interleukin-6 (IL-6) and C-reactive protein (CRP) are two that you may be familiar with.

CRP is a strong predictor of a first-time heart attack. And both are linked to cancer, Alzheimer’s, stroke and other inflammatory diseases.

Living “off your clock” also wreaks havoc on your hormones. It results in unscheduled secretion of insulin and increases markers of insulin resistance. It disrupts the production of your stress hormone, cortisol. Hunger hormones like leptin and ghrelin get thrown out of balance.

All in all, when you are not in synch with your natural cycle, your body simply can’t deal with it. Everything goes haywire. And it stays that way until you bring balance back to your inner time clock.

It’s Time to Synchronize Your Natural Circadian Rhythm

Your natural circadian rhythm synchronizes changes in gene expression that affect every aspect of your life. This includes your sleeping patterns, eating habits, energy levels, memory and behavior. It’s also what tells your heart and other organs how to adapt to all of the demands of the day.

When it’s not in alignment with its natural cycle, none of these needs can be met. As a result, maintaining healthy sleeping patterns is absolutely vital to your health.

  • When you wake up in the morning, seek light. Open the blinds and curtains. Sit outside while you sip on your tea or coffee. Enjoy breakfast on the patio. The sooner you seek light, the more effect it will have on your natural rhythm.

  • Napping feels good while you’re doing it. And just a five- or 10-minute snooze can leave you feeling like you’re starting a new day. However, it can also confuse your body and leave you tossing and turning at night. So it’s a good idea to avoid napping during the day whenever possible.

  • Eat your meals at the same time every day. Your internal clock knows when it’s time to be fed. If you put your meals off by two, three or four hours it can delay circadian-related metabolic processes by the same amount.

  • Avoid caffeinated beverages after lunchtime. You may think you’re immune to their stimulating effects… but that’s just wishful thinking.

  • Make your bedroom a sleep oasis. When darkness falls, shut the shades and turn the thermostat down a few degrees. Research has shown that 64-67 degrees Fahrenheit (really) is optimal for restful sleep. You can throw on an extra blanket if need be. Then, shut down blue light emitting devices like your phone, laptop or TV a good half hour or 45 minutes before you want to fall asleep.

  • Go to sleep and wake up as close to the same time every day.

Other than dietary and lifestyle changes, consistent sleep patterns are one of the most critical elements you can control to reset your circadian rhythm and take your health back.


The 2017 Nobel Prize in Physiology or Medicine. Press Release. Nobel Media AB 2014. Web. 5 Oct 2017.

Morris CJ, et al. Circadian misalignment increases cardiovascular disease risk factors in humans. PNAS. 2016 Mar; 113(10).

Zhang L, et. Al. Circadian rhythm and cardiovascular disorders. ChronoPhysiology and Therapy. 2014 Jul; 2014(4):27-40.

Sulli G, Lam MTY, Panda S. Interplay between Circadian Clock and Cancer: New Frontiers for Cancer Treatment. Trends Cancer. 2019 Aug;5(8):475-494.

Lopez-Minguez J, Gómez-Abellán P, Garaulet M. Timing of Breakfast, Lunch, and Dinner. Effects on Obesity and Metabolic Risk. Nutrients. 2019 Nov 1;11(11):2624.

Gnocchi D, et al. Circadian Rhythms and Hormonal Homeostasis: Pathophysiological Implications. Biology (Basel). 2017 Mar; 6(1):10. Wehrens SMT, et al. Meal Timing Regulates the Human Circadian System. Curr Biol. 2017 Jun 19;27(12):1768-1775.e3.